Can Contaminants in Drinking Water Cause Brain Damage?
The brain is one of the first organs affected by toxins, as it requires a lot of blood and its functions are delicate and intricate.
Lead
Lead poisoning typically results from ingestion of food or water contaminated with lead. It is rapidly absorbed into the bloodstream and is believed to have adverse effects on the central nervous system, the cardiovascular system, kidneys, and the immune system. If lead is detected in your drinking water, it probably originated from corrosion of your plumbing system.
Lead is a highly potent neurotoxin that accumulates in soft tissues and the bones. It can damage the nervous system, especially in young children, and cause brain disorders. The effects of lead are the same whether it enters the body through breathing or swallowing. Lead can affect almost every organ in the body although it mainly targets the nervous system.
Long-term exposure of adults can result in decreased functions of the nervous system, weakness in fingers, wrists, or ankles, increases in blood pressure, particularly in middle-aged and older people and can cause anaemia. Exposure to high levels of lead can damage the brain and kidneys in and even lead to death. High level exposures of lead have shown to reduce fertility and sperm count in males and in pregnant women, high levels of exposure may cause miscarriage. Lead has been shown many times to permanently reduce the cognitive capacity of children at extremely low levels of exposure. There appears to be no detectable lower limit below which lead has no effect on cognition. Lead is also considered to be particularly harmful for women's ability to reproduce.
Toxoplasma
Another danger is toxoplasmosis, a chlorine-resistant bacteria which causes flu-like symptoms initially, but can spread and cause devastating damage to the delicate neurological network in the brain.
It causes blindness, mental retardation and even death.

Manganese & Brain Damage
The NIEHS has supported a number of studies to better understand the potential health effects associated with exposure to manganese, an abundant metal that is found in air, water, soil, and food. These studies show that long-term occupational exposure to manganese results in irreversible damage to areas of the brain that control body movements. These findings have resulted in federal standards that limit the amount of manganese in drinking water, and new approaches for the prevention and treatment of neurological damage caused by manganese exposure.
Other studies conducted by NIEHS-supported scientists are designed to identify the underlying causes of manganese’s effects on brain function. Their research shows that manganese exposure produces the same pattern of brain cell death as that seen in PD patients. The loss of these cells results in reduction of a critical neurotransmitter called dopamine, the chemical messenger responsible for coordinated muscle movement. These insights into the impact of manganese exposure on critical brain functions will eventually pave the way for new strategies designed to protect these dopamine-producing neurons from manganese-induced damage.
Aluminum fluoride and Alzheimer's Disease
Many municipal water supplies are treated with both alum (aluminum sulfate) and fluoride. These two chemicals combine with each other easily in the blood to form aluminum fluoride. Although elemental aluminum can not pass the blood-brain barrier, some compounds such as aluminum fluoride do. Aluminum fluoride is very poorly excreted in the urine. It is poisonous to the kidneys. Aluminum salts in the brain lead to Alzheimer's Disease.
Foods, sodas and soft drinks may provide aluminum in two ways.
First, the water added may be a source of aluminum sulfate.
Second, aluminum, cans are coated with a polymer to prevent the acid of the soda from leaching the aluminum into the liquid. If the can is dented or cracked, the polymer may be broken, and the aluminum will be released into the beverage. The study, presented at the meeting here of the Society for Neuroscience, is the latest of several studies hinting at some link between aluminum in the environment and Alzheimer's disease. Several controversial studies during the last four years found that Alzheimer's disease seemed more prevalent in areas that added aluminum sulfate (alum) to the drinking water to clarify it.
Mercury
Mercury is a naturally occurring metal found throughout the environment as a result of normal breakdown of the earth's crust by wind and water. Air, water, and soil can contain mercury from both natural sources and human activity.
Long-term exposure to either inorganic or organic mercury can permanently damage the brain, kidneys, and developing fetus. The most sensitive target of low level exposure to metallic and organic mercury following short or long term exposures appears to be the nervous system. The most sensitive target of low level exposure to inorganic mercury appears to be the kidneys. Short term exposure to high levels of mercury can have similar effects.
Mercury toxicity may occur when a person is exposed to toxic amounts of mercury due to:
- Breathing airborne mercury vapors
- Eating food (usually fish or shellfish) contaminated with methylmercury
- Drinking water contaminated with mercury (a relatively rare cause of poisoning)
- Release of mercury from dental work and medical treatments
- Many dental fillings contain mercury, and under certain conditions these might release mercury vapor that could enter the bloodstream through the lungs. Removing mercury amalgam fillings during pregnancy might prove harmful because of the fetus’ special risk from elevated mercury levels in mother’s blood
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